This paper looks into the determinants of a high school’s dropout rate using panel data from 687 public high schools in Wisconsin. Using an OLS model this paper finds a few variables at the 5% significance level to have an effect on a high school’s dropout rate. A school’s funding, the racial breakdown of the student body, the education level of the local area, the unemployment rate of the local area, and the school’s student to staff ratio were all found to be significant determinants of a high school’s dropout rate. An effective initiative in bringing U.S. high school dropout rates down to those of other developed countries has the potential to save the U.S. trillions of dollars. Analyses similar to this one are the first step in achieving that goal.